INTESTINAL ATRESIAS
\ɪntˈɛstɪnə͡l atɹˈiːzi͡əz], \ɪntˈɛstɪnəl atɹˈiːziəz], \ɪ_n_t_ˈɛ_s_t_ɪ_n_əl a_t_ɹ_ˈiː_z_iə_z]\
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Congenital obliteration of the lumen of the intestine, with the ileum involved in 50% of the cases and the jejunum and duodenum following in frequency. It is the most frequent cause of intestinal obstruction in the newborn infant. Its etiology may be related to failure of recanalization during early development or to some impairment of blood supply during intrauterine life. (From Stedman, 25th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.