INTEGRIN ALPHAVBETA3
\ɪntˈɛɡɹɪn ˈalfəvbˌɛtə θɹˈiː], \ɪntˈɛɡɹɪn ˈalfəvbˌɛtə θɹˈiː], \ɪ_n_t_ˈɛ_ɡ_ɹ_ɪ_n ˈa_l_f_ə_v_b_ˌɛ_t_ə θ_ɹ_ˈiː]\
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alpha-v beta-3 INTEGRINS that bind vitronectin with high affinity and play a role in cell migration. They also bind fibrinogen, von Willebrand factor, osteopontin, and thrombospondin. The highly homologous alpha-v beta-5 integrin also binds vitronectin, but mediates simple adhesion.
By DataStellar Co., Ltd
