\ɪntˈɛɡɹɪnz], \ɪntˈɛɡɹɪnz], \ɪ_n_t_ˈɛ_ɡ_ɹ_ɪ_n_z]\
Definitions of INTEGRINS
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A family of transmembrane glycoproteins consisting of noncovalent heterodimers. They interact with a wide variety of ligands including extracellular matrix glycoproteins, complement, and other cells, while their intracellular domains interact with the cytoskeleton. The integrins consist of at least three identified families: the cytoadhesin receptors, the leukocyte adhesion receptors, and the very-late-antigen receptors. Each family contains a common beta-subunit combined with one or more distinct alpha-subunits. These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development, hemostasis, thrombosis, wound healing, immune and nonimmune defense mechanisms, and oncogenic transformation.
By DataStellar Co., Ltd
Word of the day
- lunar calendar used by Moslems; dates from 622 AD (Hegira); beginning of the Moslem retrogresses through solar year completing cycle every 32 years lunar calendar used by Muslims; dates from 622 AD (Hegira); beginning of the Muslim year retrogresses through solar completing cycle every 32 years