INCLUSION BODY MYOPATHY, SPORADIC
\ɪnklˈuːʒən bˈɒdi ma͡ɪˈɒpəθɪ], \ɪnklˈuːʒən bˈɒdi maɪˈɒpəθɪ], \ɪ_n_k_l_ˈuː_ʒ_ə_n b_ˈɒ_d_i m_aɪ_ˈɒ_p_ə_θ_ɪ]\
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Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)
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