IMMUNOGLOBULIN CONSTANT REGION
\ɪmjˈuːnəɡlˌɒbjʊlˌɪn kˈɒnstənt ɹˈiːd͡ʒən], \ɪmjˈuːnəɡlˌɒbjʊlˌɪn kˈɒnstənt ɹˈiːdʒən], \ɪ_m_j_ˈuː_n_ə_ɡ_l_ˌɒ_b_j_ʊ_l_ˌɪ_n k_ˈɒ_n_s_t_ə_n_t ɹ_ˈiː_dʒ_ə_n]\
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That region of the immunoglobulin (antibody) molecule that is invariable in its amino acid sequence within any class of immunoglobulins. It confers the biological specificity to the Ig and is grossly species specific. It comprises the C-terminus half of the light chains and three quarters or more of the heavy chains, all of the Fc fragment, and the C-terminus half of the Fab fragment.
By DataStellar Co., Ltd
