HYDRORACHIS
\hˌa͡ɪdɹɔːɹˈat͡ʃɪz], \hˌaɪdɹɔːɹˈatʃɪz], \h_ˌaɪ_d_ɹ_ɔː_ɹ_ˈa_tʃ_ɪ_z]\
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An effusion of serum, often owing to inflammation of the spinal membranes and forming a soft, frequently transparent, tumour, constituted of the membranes of the spinal marrow, which are distended and projecting backwards from the vertebral canal, the posterior paries of which, when the affection is congenital, is wanting to a certain extent. The disease is often accompanied with paralysis of the lower extremities. It is congenital, and situate in the lumbar or sacral regions. It is almost always fatal: - the tumour rupturing, and death occurring instantaneously. On dissection, a simple separation or complete absence of the spinous processes of the vertebrae is perceived, with, at times, destruction or absence of spinal marrow. The treatment is the same as in hydrocephalus chroniccus; and, as in it, advantage seems occasionally to have been derived by puncturing with a fine needle.
By Robley Dunglison
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.