HEME OXYGENASE (DECYCLIZING)
\hˈiːm ˈɒksɪd͡ʒənˌe͡ɪs dɪsˈa͡ɪkə͡lˌa͡ɪzɪŋ], \hˈiːm ˈɒksɪdʒənˌeɪs dɪsˈaɪkəlˌaɪzɪŋ], \h_ˈiː_m ˈɒ_k_s_ɪ_dʒ_ə_n_ˌeɪ_s__ d_ɪ_s_ˈaɪ_k_əl_ˌaɪ_z_ɪ_ŋ]\
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A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt. EC 1.14.99.3.
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