HEME CONTROLLED TRANSLATIONAL REPRESSOR
\hˈiːm kəntɹˈə͡ʊld tɹanslˈe͡ɪʃənə͡l ɹɪpɹˈɛsə], \hˈiːm kəntɹˈəʊld tɹanslˈeɪʃənəl ɹɪpɹˈɛsə], \h_ˈiː_m k_ə_n_t_ɹ_ˈəʊ_l_d t_ɹ_a_n_s_l_ˈeɪ_ʃ_ə_n_əl ɹ_ɪ_p_ɹ_ˈɛ_s_ə]\
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A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- heme
- heme aa3 cytochrome oxidase
- heme b
- heme controlled inhibitor
- heme controlled repressor
- Heme Controlled Translational Repressor
- heme oxygenase
- heme oxygenase (decyclizing)
- heme protein
- heme regulated eif 2alpha kinase
- heme synthetase