GAMMA AMINOBUTYRIC ACID MODULATORS
\ɡˈaməɹ ɐmˌɪnəbjuːtˈɪɹɪk ˈasɪd mˈɒdjʊlˌe͡ɪtəz], \ɡˈaməɹ ɐmˌɪnəbjuːtˈɪɹɪk ˈasɪd mˈɒdjʊlˌeɪtəz], \ɡ_ˈa_m_ə_ɹ ɐ_m_ˌɪ_n_ə_b_j_uː_t_ˈɪ_ɹ_ɪ_k ˈa_s_ɪ_d m_ˈɒ_d_j_ʊ_l_ˌeɪ_t_ə_z]\
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Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. General anesthetics probably act at least partly by potentiating GABAergic responses, but they are not included here.
By DataStellar Co., Ltd
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basidiomycota
- comprises fungi bearing the spores on basidium: Gasteromycetes (puffballs); Tiliomycetes (comprising orders Ustilaginales (smuts) and Uredinales (rusts)); Hymenomycetes (mushrooms; toadstools; agarics; bracket fungi); in some classification systems considered a division of kingdom comprises fungi bearing spores on a basidium; includes Gasteromycetes (puffballs) Tiliomycetes comprising the orders Ustilaginales (smuts) and Uredinales (rusts) Hymenomycetes (mushrooms, toadstools, agarics bracket fungi).
Nearby Words
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