CYTOCHROME P 450 LM(4)
\sˈa͡ɪtəkɹˌə͡ʊm pˈiː fˈɔːhˈʌndɹədən fˈɪfti ˌɛlˈɛm fˈɔː], \sˈaɪtəkɹˌəʊm pˈiː fˈɔːhˈʌndɹədən fˈɪfti ˌɛlˈɛm fˈɔː], \s_ˈaɪ_t_ə_k_ɹ_ˌəʊ_m p_ˈiː f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɪ_f_t_i_ ˌɛ_l_ˈɛ_m__ f_ˈɔː]\
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A polycyclic aromatic hydrocarbon-inducible cytochrome which is of significant clinical interest due to the large number of drug interactions associated with induction and inhibition of theophylline. Caffeine is considered to be a model substrate for this enzyme. It also metabolizes theophylline and antipyrene. Environmental factors including cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole produce increases in CYP1A2 activity. (Ann Pharmacother 1995;29:619-24) EC 1.-.
By DataStellar Co., Ltd
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Nearby Words
- cytochrome p 450 cyp2e1
- cytochrome p 450 cyp7
- cytochrome p 450 dependent monooxygenase
- cytochrome p 450 dependent o dealkylase
- cytochrome p 450 iie1
- Cytochrome P 450 LM(4)
- cytochrome p 450 monooxygenase
- cytochrome p 450 oxidase
- cytochrome p 450 oxygenase
- cytochrome p 450(11 beta)
- cytochrome p 450(arom)