CORTICOTROPHIN (1 39)
\kˈɔːtɪkˌɒtɹəfˌɪn wˈɒn θˈɜːtinˈa͡ɪn], \kˈɔːtɪkˌɒtɹəfˌɪn wˈɒn θˈɜːtinˈaɪn], \k_ˈɔː_t_ɪ_k_ˌɒ_t_ɹ_ə_f_ˌɪ_n__ w_ˈɒ_n θ_ˈɜː_t_i_n_ˈaɪ_n]\
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Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)
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