CD117 ANTIGENS
\sˌiːdˈiː wˈɒnhˈʌndɹədən sˈɛvəntˌiːn ˈantɪd͡ʒˌɛnz], \sˌiːdˈiː wˈɒnhˈʌndɹədən sˈɛvəntˌiːn ˈantɪdʒˌɛnz], \s_ˌiː_d_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɛ_v_ə_n_t_ˌiː_n ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.
By DataStellar Co., Ltd
