CARDIAC DEPRESSANTS
\kˈɑːdɪˌak dɪpɹˈɛsənts], \kˈɑːdɪˌak dɪpɹˈɛsənts], \k_ˈɑː_d_ɪ__ˌa_k d_ɪ_p_ɹ_ˈɛ_s_ə_n_t_s]\
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Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
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