C REL PROTEINS
\sˈiː ɹˈɛl pɹˈə͡ʊtiːnz], \sˈiː ɹˈɛl pɹˈəʊtiːnz], \s_ˈiː ɹ_ˈɛ_l p_ɹ_ˈəʊ_t_iː_n_z]\
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Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.
By DataStellar Co., Ltd
