APC GENES
\ˌe͡ɪpˌiːsˈiː d͡ʒˈiːnz], \ˌeɪpˌiːsˈiː dʒˈiːnz], \ˌeɪ_p_ˌiː_s_ˈiː dʒ_ˈiː_n_z]\
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Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
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