ANTICHOLINESTERASE DRUGS
\ˌantɪkˈɒla͡ɪnstəɹˌe͡ɪz dɹˈʌɡz], \ˌantɪkˈɒlaɪnstəɹˌeɪz dɹˈʌɡz], \ˌa_n_t_ɪ_k_ˈɒ_l_aɪ_n_s_t_ə_ɹ_ˌeɪ_z d_ɹ_ˈʌ_ɡ_z]\
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Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
By DataStellar Co., Ltd
