ANCILLARY ATTACHMENT

\ˈansɪləɹi ɐtˈat͡ʃmənt], \ˈansɪləɹi ɐtˈat‍ʃmənt], \ˈa_n_s_ɪ_l_ə_ɹ_i_ ɐ_t_ˈa_tʃ_m_ə_n_t]\

Definitions of ANCILLARY ATTACHMENT

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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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