A1PI
\ˌe͡ɪ wˈɒn pˈa͡ɪ], \ˌeɪ wˈɒn pˈaɪ], \ˌeɪ w_ˈɒ_n p_ˈaɪ]\
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Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (A1PI), it exists in over 30 different biochemical variant forms known collectively as the Pi (protease inhibitor) system. Hereditary A1PI deficiency is associated with pulmonary emphysema.
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