RADIOIMMUNOCONJUGATES
\ɹˌe͡ɪdɪə͡ʊɪmjˈuːnəkˌɒnd͡ʒuːɡˌe͡ɪts], \ɹˌeɪdɪəʊɪmjˈuːnəkˌɒndʒuːɡˌeɪts], \ɹ_ˌeɪ_d_ɪ__əʊ_ɪ_m_j_ˈuː_n_ə_k_ˌɒ_n_dʒ_uː_ɡ_ˌeɪ_t_s]\
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Combinations of diagnostic or therapeutic substances linked with specific immune substances such as immunoglobulins, monoclonal antibodies or antigens. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of drugs and radioisotopes in the chemotherapy and radioimmunotherapy of certain cancers.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.