INCLUSION BODY MYOSITIS
\ɪnklˈuːʒən bˈɒdi mˌa͡ɪəsˈa͡ɪtɪs], \ɪnklˈuːʒən bˈɒdi mˌaɪəsˈaɪtɪs], \ɪ_n_k_l_ˈuː_ʒ_ə_n b_ˈɒ_d_i m_ˌaɪ_ə_s_ˈaɪ_t_ɪ_s]\
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myositis characterized by weakness of limb muscles (especially the thighs and wrists and fingers); sometimes involves swallowing muscles; onset after 50 and slowly progressive; seen more often in men than in women
By Princeton University
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Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)
By DataStellar Co., Ltd
