CHORIONIC GONADOTROPIN RECEPTOR
\kˌɔːɹɪˈɒnɪk ɡˈɒnɐdˌɒtɹəpˌɪn ɹɪsˈɛptə], \kˌɔːɹɪˈɒnɪk ɡˈɒnɐdˌɒtɹəpˌɪn ɹɪsˈɛptə], \k_ˌɔː_ɹ_ɪ__ˈɒ_n_ɪ_k ɡ_ˈɒ_n_ɐ_d_ˌɒ_t_ɹ_ə_p_ˌɪ_n ɹ_ɪ_s_ˈɛ_p_t_ə]\
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Those protein complexes or molecular sites on the surfaces and cytoplasm of gonadal cells that bind luteinizing or chorionic gonadotropic hormones and thereby cause the gonadal cells to synthesize and secrete sex steroids. The hormone-receptor complex is internalized from the plasma membrane and initiates steroid synthesis.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.