ANTIBODY DEPENDENT CELL CYTOTOXICITY
\ˈantɪbˌɒdi dɪpˈɛndənt sˈɛl sˌa͡ɪtətəksˈɪsɪti], \ˈantɪbˌɒdi dɪpˈɛndənt sˈɛl sˌaɪtətəksˈɪsɪti], \ˈa_n_t_ɪ_b_ˌɒ_d_i d_ɪ_p_ˈɛ_n_d_ə_n_t s_ˈɛ_l s_ˌaɪ_t_ə_t_ə_k_s_ˈɪ_s_ɪ_t_i]\
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The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- antibody binding site
- antibody binding sites
- antibody deficiency syndrome
- antibody deficiency syndromes
- antibody dependent cell cytotoxicities
- Antibody Dependent Cell Cytotoxicity
- antibody dependent cell cytoxicities
- antibody dependent cell cytoxicity
- antibody dependent enhancement
- antibody dependent enhancements
- antibody diversities