TOXIC MEGACOLON

\tˈɒksɪk mˈɛɡəkˌɒlən], \tˈɒksɪk mˈɛɡəkˌɒlən], \t_ˈɒ_k_s_ɪ_k m_ˈɛ_ɡ_ə_k_ˌɒ_l_ə_n]\

Definitions of TOXIC MEGACOLON

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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