STRIATONIGRAL DEGENERATIONS

\stɹˈa͡ɪɐtˌɒnɪɡɹə͡l dɪd͡ʒˌɛnəɹˈe͡ɪʃənz], \stɹˈa‍ɪɐtˌɒnɪɡɹə‍l dɪd‍ʒˌɛnəɹˈe‍ɪʃənz], \s_t_ɹ_ˈaɪ__ɐ_t_ˌɒ_n_ɪ_ɡ_ɹ_əl d_ɪ_dʒ_ˌɛ_n_ə_ɹ_ˈeɪ_ʃ_ə_n_z]\

Definitions of STRIATONIGRAL DEGENERATIONS

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2010 - Medical Dictionary Database
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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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