STRIATONIGRAL ATROPHY

\stɹˈa͡ɪɐtˌɒnɪɡɹə͡l ˈatɹəfi], \stɹˈa‍ɪɐtˌɒnɪɡɹə‍l ˈatɹəfi], \s_t_ɹ_ˈaɪ__ɐ_t_ˌɒ_n_ɪ_ɡ_ɹ_əl ˈa_t_ɹ_ə_f_i]\

Definitions of STRIATONIGRAL ATROPHY

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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