STEAK AU POIVRE
\stˈe͡ɪk ˌə͡ʊ pˈɔ͡ɪvə], \stˈeɪk ˌəʊ pˈɔɪvə], \s_t_ˈeɪ_k ˌəʊ p_ˈɔɪ_v_ə]\
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By Princeton University
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.