SAINT LEONARD'S, CLIMATE OF
\sˈe͡ɪnt lˈɛnədz], \sˈeɪnt lˈɛnədz], \s_ˈeɪ_n_t l_ˈɛ_n_ə_d_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.