\ɹɪfˈɜːɹəbə͡l], \ɹɪfˈɜːɹəbəl], \ɹ_ɪ_f_ˈɜː_ɹ_ə_b_əl]\
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(usually followed by `to') able to be assigned or credited to; "punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him"; "decide to which of these motives such extraordinary scenes are referable"- Charles Dickens
By Princeton University
By William Hand Browne, Samuel Stehman Haldeman
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.