PURPLE CURVE EFFECT
\pˈɜːpə͡l kˈɜːv ɪfˈɛkt], \pˈɜːpəl kˈɜːv ɪfˈɛkt], \p_ˈɜː_p_əl k_ˈɜː_v ɪ_f_ˈɛ_k_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.