PRIMITIVE CARDIAC TISSUE
\pɹˈɪmɪtˌɪv kˈɑːdɪˌak tˈɪʃuː], \pɹˈɪmɪtˌɪv kˈɑːdɪˌak tˈɪʃuː], \p_ɹ_ˈɪ_m_ɪ_t_ˌɪ_v k_ˈɑː_d_ɪ__ˌa_k t_ˈɪ_ʃ_uː]\
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.