POEMS SYNDROME
\pˈə͡ʊɪmz sˈɪndɹə͡ʊm], \pˈəʊɪmz sˈɪndɹəʊm], \p_ˈəʊ_ɪ_m_z s_ˈɪ_n_d_ɹ_əʊ_m]\
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A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18 (7):553-62)
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Nearby Words
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