NK CELLS
\ˌɛnkˈe͡ɪ sˈɛlz], \ˌɛnkˈeɪ sˈɛlz], \ˌɛ_n_k_ˈeɪ s_ˈɛ_l_z]\
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Cells responsible for spontaneous cytotoxicity of a variety of tumor cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as KILLER CELLS (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.