INTRAOSSEOUS INFUSION
\ˌɪntɹəɹˈɒsi͡əs ɪnfjˈuːʒən], \ˌɪntɹəɹˈɒsiəs ɪnfjˈuːʒən], \ˌɪ_n_t_ɹ_ə_ɹ_ˈɒ_s_iə_s ɪ_n_f_j_ˈuː_ʒ_ə_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.