INNOMINATA ARTERIA

\ɪnnˌɒmɪnˈɑːtəɹ ɑːtˈi͡əɹɪə], \ɪnnˌɒmɪnˈɑːtəɹ ɑːtˈi‍əɹɪə], \ɪ_n_n_ˌɒ_m_ɪ_n_ˈɑː_t_ə_ɹ ɑː_t_ˈiə_ɹ_ɪ__ə]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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