HYPERTENSIVE ENCEPHALOPATHY
\hˈa͡ɪpətənsˌɪv ɛnsˌɛfɐlˈɒpəθɪ], \hˈaɪpətənsˌɪv ɛnsˌɛfɐlˈɒpəθɪ], \h_ˈaɪ_p_ə_t_ə_n_s_ˌɪ_v ɛ_n_s_ˌɛ_f_ɐ_l_ˈɒ_p_ə_θ_ɪ]\
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Brain dysfunction or damage resulting from MALIGNANT HYPERTENSION, usually associated with a diastolic blood pressure in excess of 125 mmHg. Clinical manifestations include headache, nausea, emesis, seizures, altered mental status (in some cases progressing to COMA); PAPILLEDEMA; and RETINAL HEMORRHAGE. Focal neurologic signs may develop. Pathologically, this condition may be associated with the formation of ischemic lesions in the brain (BRAIN ISCHEMIA).
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- hypertension edema proteinuria gestosis
- hypertension, pulmonary, of newborn, persistent
- hypertensive
- hypertensive cerebral hemorrhage
- hypertensive cerebral hemorrhages
- Hypertensive Encephalopathy
- hypertensive intracerebral hemorrhage
- hypertensive intracerebral hemorrhages
- hypertensive intracranial hemorrhage
- hypertensive intracranial hemorrhages
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