Definitions of GABA(A) Receptor

  1. Cell surface proteins which bind GAMMA- AMINOBUTYRIC ACID and control an integral membrane chloride channel. GABA- A receptors are the most prevalent inhibitory neurotransmitter receptors in the brain. Several isoforms have been cloned, and they belong to a superfamily which includes nicotinic receptors, glycine receptors, and 5HT- 3 receptors. Most GABA- A receptors have separate modulatory sites sensitive to benzodiazepines and to barbiturates.