EUKARYOTIC INITIATION FACTOR 2B

\jˌuːkɐɹɪˈɒtɪk ɪnˌɪʃɪˈe͡ɪʃən fˈaktə tˈuː bˈiː], \jˌuːkɐɹɪˈɒtɪk ɪnˌɪʃɪˈe‍ɪʃən fˈaktə tˈuː bˈiː], \j_ˌuː_k_ɐ_ɹ_ɪ__ˈɒ_t_ɪ_k ɪ_n_ˌɪ_ʃ_ɪ__ˈeɪ_ʃ_ə_n f_ˈa_k_t_ə t_ˈuː b_ˈiː]\

Definitions of EUKARYOTIC INITIATION FACTOR 2B

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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