DISTAL THROMBUS

\dɪstˈal θɹˈɒmbəs], \dɪstˈal θɹˈɒmbəs], \d_ɪ_s_t_ˈa_l θ_ɹ_ˈɒ_m_b_ə_s]\

Definitions of DISTAL THROMBUS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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