\kˈɒlɐlˌɪsa͡ɪn], \kˈɒlɐlˌɪsaɪn], \k_ˈɒ_l_ɐ_l_ˌɪ_s_aɪ_n]\
Definitions of COLLALYSINE
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A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 184.108.40.206.
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