COLD INSOLUBLE GLOBULINS
\kˈə͡ʊld ɪnsˈɒljuːbə͡l ɡlˈɒbjʊlˌɪnz], \kˈəʊld ɪnsˈɒljuːbəl ɡlˈɒbjʊlˌɪnz], \k_ˈəʊ_l_d ɪ_n_s_ˈɒ_l_j_uː_b_əl ɡ_l_ˈɒ_b_j_ʊ_l_ˌɪ_n_z]\
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Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
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