CLOSTRIDIUM BOTULINUM TOXINS
\kləstɹˈɪdi͡əm bˈɒtjʊlˌɪnəm tˈɒksɪnz], \kləstɹˈɪdiəm bˈɒtjʊlˌɪnəm tˈɒksɪnz], \k_l_ə_s_t_ɹ_ˈɪ_d_iə_m b_ˈɒ_t_j_ʊ_l_ˌɪ_n_ə_m t_ˈɒ_k_s_ɪ_n_z]\
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Toxins produced by Clostridium botulinum. There are at least seven different substances, most being proteins. They have neuro-, entero-, and hemotoxic properties, are immunogenic, and include the most potent poisons known. The most commonly used apparently blocks release of acetylcholine at cholinergic synapses.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.