CHLORMETHIAZOLE
\klˈɔːɹəmˌɛθɪˌazə͡ʊl], \klˈɔːɹəmˌɛθɪˌazəʊl], \k_l_ˈɔː_ɹ_ə_m_ˌɛ_θ_ɪ__ˌa_z_əʊ_l]\
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A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.