ARCHAEAL TOPOISOMERASE 1
\ɑːkˈi͡əl tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪz wˈɒn], \ɑːkˈiəl tˈɒpɔɪsˌəʊmɹeɪz wˈɒn], \ɑː_k_ˈiə_l t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z w_ˈɒ_n]\
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Archaeal enzymes of the DNA TOPOISOMERASES TYPE I class that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These archaeal enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
By DataStellar Co., Ltd
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