WEGENER GRANULOMATOSIS
\wˈɛd͡ʒənə ɡɹˌanjʊlˌɒmɐtˈə͡ʊsɪs], \wˈɛdʒənə ɡɹˌanjʊlˌɒmɐtˈəʊsɪs], \w_ˈɛ_dʒ_ə_n_ə ɡ_ɹ_ˌa_n_j_ʊ_l_ˌɒ_m_ɐ_t_ˈəʊ_s_ɪ_s]\
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A multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (Dorland, 27th ed)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- weezel
- weft
- weftage
- wefte
- wegener
- Wegener Granulomatosis
- wegeners granulomatosis
- wegner's disease
- wegner's disease's sign
- wegotism
- wehadinc