VESIVIRUSES
\vˈɛsɪvˌa͡ɪɹəsɪz], \vˈɛsɪvˌaɪɹəsɪz], \v_ˈɛ_s_ɪ_v_ˌaɪ_ɹ_ə_s_ɪ_z]\
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A genus of the family CALICIVIRIDAE comprised of species infecting a wide range of organisms. Most members of this genus can be readily propagated in cell culture (as opposed to other genera of Caliciviridae). The type species is VESICULAR EXANTHEMA OF SWINE VIRUS.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.