TOCOLYTIC AGENTS
\tˌɒkəlˈɪtɪk ˈe͡ɪd͡ʒənts], \tˌɒkəlˈɪtɪk ˈeɪdʒənts], \t_ˌɒ_k_ə_l_ˈɪ_t_ɪ_k ˈeɪ_dʒ_ə_n_t_s]\
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Drugs that prevent preterm labor and immature birth by suppressing uterine contractions. Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.