SYPHILITIC CHANCRE
\sˌa͡ɪfɪlˈɪtɪk t͡ʃˈankə], \sˌaɪfɪlˈɪtɪk tʃˈankə], \s_ˌaɪ_f_ɪ_l_ˈɪ_t_ɪ_k tʃ_ˈa_n_k_ə]\
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The local manifestation of syphilitic infection at the site of its inoculation, characterized by a circumscribed induration. [Fr.]
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.