SHIGA TOXINS
\ʃˈiːɡə tˈɒksɪnz], \ʃˈiːɡə tˈɒksɪnz], \ʃ_ˈiː_ɡ_ə t_ˈɒ_k_s_ɪ_n_z]\
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A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.
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