RELATIVE BIOLOGICAL EFFECTIVENESS

\ɹˈɛlətˌɪv bˌa͡ɪəlˈɒd͡ʒɪkə͡l ɪfˈɛktɪvnəs], \ɹˈɛlətˌɪv bˌa‍ɪəlˈɒd‍ʒɪkə‍l ɪfˈɛktɪvnəs], \ɹ_ˈɛ_l_ə_t_ˌɪ_v b_ˌaɪ_ə_l_ˈɒ_dʒ_ɪ_k_əl ɪ_f_ˈɛ_k_t_ɪ_v_n_ə_s]\

Definitions of RELATIVE BIOLOGICAL EFFECTIVENESS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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