PYCNOSPHYGMIA

\pˌɪknəsfˈɪɡmi͡ə], \pˌɪknəsfˈɪɡmi‍ə], \p_ˌɪ_k_n_ə_s_f_ˈɪ_ɡ_m_iə]\

Definitions of PYCNOSPHYGMIA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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